(Sr.) Technician Process Development (USP)

Work for an Organization that brings innovative therapies to patients worldwide.

VectorY combines the potential of antibodies and gene therapy to develop long-lasting therapeutic solutions for disease areas of high unmet medical need.

Founded in August 2020, and based in the Amsterdam Science Park, VectorY is a fully integrated gene therapy company focused on the development of innovative therapeutics.

With R&D and manufacturing facilities in Amsterdam, VectorY develops proprietary & partnered programs based on its novel AAV-based vectorized antibody gene therapy platform. Next generation vector technologies are applied to develop product candidates, which will enable a proprietary and highly scalable manufacturing process within VectorY’s own manufacturing facilities.

Your position within the organization

The Process Development (PD) department is an essential part of VectorY, which is taking the lead for the in-house development, scale-up and manufacture of novel gene therapies. The upstream processing (USP) team is responsible for the development of the fermentation process, securing the biopharmaceutical produced at high yield and product quality. The USP team will also support tech-transfer to Contract Manufacturing Organisations (CMOs) to support the manufacture of AAV-based gene therapies for clinical trials. 

Main responsibilities of the role:

  • As a (Sr) Technician, you are involved in the practical day-to-day lab work, data analysis and reporting of results

  • The (Sr) Technician prepares, plans and executes experimental work related to Upstream Bioprocessing, such as shake flask Design of Experiment (DoE) studies, and Rocking Motion and Stirred Tank Reactor development activities; these activities will be supported by the Scientist Upstream Process Development

  • The (Sr) Technician is involved in the operation and maintenance of small and pilot scale laboratory equipment 

  • The role will also include time to provide analytical support (analysis of in-process samples and final drug substance) to support development programs

  • Communicates the daily work and results obtained to the Scientist Upstream Process Development; presentation of work to internal stakeholders

Skills and Qualifications: 

  • MSc, or HBO/BSc, or equivalent, with a minimum of 2 years of relevant working experience in industry or academia.

  • Hands on experience with animal/insect cell culture, viral handlings, Rocking Motion / Stirred Tank Bioreactors

  • Familiarity with analytical methods, such as TCID50, (q)PCR, SDS-PAGE, BCA assays, ELISAs is a plus

Your Natural Strengths and Drivers

You are thorough and have an eye for detail. You deliver highly precise work and work consistently and in a steady pace and are a team player.

Working at VectorY

We offer a personal and authentic experience within a young, ambitious biotech company on the path to bring innovative therapies to patients worldwide. 
For more information: sandra.lemmens@vectorytx.com