Technology Transfer Specialist

Work for an Organization that brings innovative therapies to patients worldwide.

Founded in August 2020, and based in the Amsterdam Science Park, VectorY focuses on the development of innovative therapeutics. VectorY combines the potential of antibodies and gene therapy to develop long-lasting therapeutic solutions to treat neurodegenerative diseases such as ALS and Huntington’s Disease.

Job description:

VectorY is seeking a highly motivated individual to join us as a Technology Transfer Specialist to support the process transfer activities from VectorY R&D to an external GMP manufacturing facility as well as overseeing the GMP operations. The processes for production of cell banks, baculovirus seeds and adeno-associated virus (AAV) drug substance are developed at VectorY and subsequently transferred to our CDMO in Belgium for scale-up and GMP production of batches for clinical studies. The role is to be the connection between sending and receiving sites on technical and organizational level. The job requires good knowledge of biopharmaceutical manufacturing processes for viral vectors. Additionally, pro-active cooperation and clear communication with colleagues at VectorY and the external partner is essential.

Responsibilities:

  • Responsible for the technology transfer of the processes from VectorY to the external manufacturing facility (Upstream & Downstream process, Assays).

  • Responsible for successful execution of CDMO GMP manufacturing operations, resulting in release of VectorY cell banks, master virus seeds and AAV Drug Substance/Drug Product.

  • Acts as liaison between VectorY and CDMO, including regular on-site representation of VectorY at the CDMO in Belgium.

  • Manage and execute the operational project activities related to the technology transfer and GMP production.

  • Structure the technology transfer by using appropriate tools such as gap analysis, risk assessment and/or technology transfer protocol.

  • Co-ordinate and participate in tech transfer meetings.

  • Lead technical meetings and coordinate execution of tech transfer and GMP production deliverables.

  • Oversee adherence to program timelines and budget.

  • Report on the progress of technology transfer tasks and perform data analysis.

  • Control data and material exchange between sending and receiving site.

  • Train development staff in best-practices to develop GMP compliant processes.

Profile:

  • Strong interpersonal skills – able to work effectively with operational staff and project management.

  • Knowledge of technology transfer and GMP pharmaceutical processes and scale-up and guidelines/regulations.

  • Master degree and/or experience level in life science.

  • Fluent in English and good communication skills.

  • At least 5 years relevant work experience in an industry setting, preferably with viral vectored pharmaceutical product candidates.

Interested?

Please send your application to talent.acquisition@vectorytx.com to the attention of Sandra Lemmens.